By itself doubled in a 10-year period, between 1996 and 2005. At the same time, research has shown that SSRI make use of is linked to a genuine number of illnesses and conditions, including increased threat of heart and stroke disease, as well as – oddly enough – psychological problems, many of that have led to suicide.. Antidepressants increase the risk of breast cancer Women who take an SSRI – selective serotonin reuptake inhibitor – antidepressant have a higher threat of developing breast malignancy, according to a meta-analysis of 61 individual research indicated. ‘Reviewing the data is a critical public health issue in light of the increasing prevalence of antidepressant use, especially among women, and in light to the fact that one in eight women will be identified as having cancer of the breasts during their lifetime,’ said the scholarly study, according to a report from the Alliance for Human Research Protection.This REMS plan is designed to judge and mitigate known and potential dangers and serious adverse occasions; to see healthcare companies about how to correctly inject XIAFLEX and perform finger expansion procedures; and, to see patients about the critical risks connected with XIAFLEX. Pfizer, Inc., Auxilium’s advertising partner for XIAFLEX in European countries, has mentioned that the scientific/technical review process of the Marketing Authorization Authorization for XIAFLEX in European countries started in January 2010. Pfizer is in charge of advertising XIAFLEX for Dupuytren’s contracture and Peyronie’s disease in 27 member countries of EU and 19 various other European and Eurasian countries.